We generally don't recommend mixing caffeine and collagen, or consuming them within a few hours of each other. This is because caffeine can suppress collagen production by preventing cell growth and interfering with the development of cartilage. As a result, this affects the ability to make new collagen and the genes involved in maturing cartilage cells.
However, whether you're a coffee drinker or not, we still believe that it is important to supplement with collagen. We recommend taking collagen before working out. If eliminating caffeine in the mornings or pre-workout seems impossible, wait a few hours after any caffeine consumption before taking collagen, or move it into your bedtime routine.